December 21 in the history of the Birmingham District:
- 2011: Charles Samuels was appointed director of the U. S. Bureau of Prisons.
- 2010: James Head, founder of James A. Head & Company and notable civic leader, died.
- 2001: Alabama Crimson Tide football star Ed Salem died.
- 1993: Radio announcer Joe Rumore died.
- 1990: Chan Gailey was named head coach of the Birmingham Fire.
- 1989: Heisman Trophy winner Mark Ingram was born in Hackensack, New Jersey.
- 1974: A Kenny Stabler pass into a "sea of hands" was secured by Clarence Davis for a game-winning Raiders touchdown in an NFL playoff game against the reigning Miami Dolphins.
- 1924: University of Alabama administrator John Blackburn was born in Malta Bend, Missouri.
- 1912: Former Mayor of Birmingham Mel Drennen married Eloise August Johnson in New York City.
- 1902: Streetcar service on the No. 5 Ensley line began.
- 1898: Educator A. H. Parker, twice-widowed, married Anna Gilbert.
- 1886: Attorney Mitchell A. Porter married Hattie Earle of Tyler, Texas.
- 1868: Former University of Alabama president Basil Manly died in South Carolina.